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Back|NCT05237258Recruiting
Official Title

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

Sponsor
Massachusetts General Hospital
Enrollment
2,300
Timeline
Jun 2022 → Apr 2029
About This Study

This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute myeloid leukemia (AML).

Eligibility Criteria

Inclusion Criteria

  • 1Hospitalized patients (age ≥ 18 years) with high-risk AML defined as:
  • 2Patients with new diagnosis ≥ 60 years of age
  • 3An antecedent hematologic disorder
  • 4Therapy related-disease
  • 5Relapsed or primary refractory AML
  • 6Within five business days of initiating therapy with either a) intensive chemotherapy (7+3) or modification of this regimen on a clinical trial, or a similar intensive regimen requiring prolonged hospitalization; or b) hypomethylating agents +/- additional agents or modification of this regimen on a clinical trial.
  • 7Adult (≥18 years) relative or friend of a participating patient who the patient identifies as living with or has in-person contact with them at least twice per week.

Exclusion Criteria

  • 1Patients with a diagnosis of acute promyelocytic leukemia (APML)
  • 2Patients with AML receiving supportive care alone
  • 3Patients with psychiatric or cognitive conditions which the treating clinicians believe prohibits informed consent or compliance with study procedures
  • 4Patients seen by a palliative care clinician (MD, DO, APP) during two previous hospitalizations in the six months prior to enrollment
  • 5Patients expected to be discharged within 2 days

Locations

20 sites participating in this study

Emory University

Atlanta, Georgia 30322

Recruiting

Dio Kavalieratos, MD

d.kavalieratos@emory.edu

University of Alabama - Birmingham

Birmingham, Alabama 35294

Recruiting

Richard Taylor, PhD

rtaylor@uabmc.edu

Stanford University

Stanford, California 94305

Recruiting

Karl Lorenz, MD

kalorenz@stanford.edu
Data sourced from ClinicalTrials.govView on ClinicalTrials.gov →