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Official Title

Feasibility and Acceptability of an Individualized Online Home-Based Exercise Program on Psychoneurological Symptoms in Gynecologic Cancer Survivors: A Pilot Study

Sponsor
Emory University
Enrollment
40
Timeline
Sep 2025 → Jul 2027
About This Study

This clinical trial tests an individualized online home-based exercise program in gynecologic cancer survivors and its impact on gut microbiome (the bacteria and microorganisms that live in the digestive system) and symptoms such as pain, fatigue, sleep disturbance, depression, and cognitive impairment. These symptoms can significantly reduce the quality of life (QoL) and survival rate in this cancer population. Thus, promoting physical activity among cancer survivors may help mitigate these severe symptoms. Using online platforms such as Zoom can help participants access an individualized exercise program that meets their specific needs to engage in physical activity and decrease their symptom burden. Home-based exercise, by providing self-chosen time and location and low costs, can address some barriers to physical activity for cancer survivors. An individualized online home-based exercise program may be feasible, and may improve symptoms and quality of life in gynecologic cancer survivors.

Eligibility Criteria

Inclusion Criteria

  • 1Women aged ≥ 18 years old
  • 2Previously diagnosed with gynecologic cancer (e.g., uterine, ovarian, cervical)
  • 3Completed cancer treatment (chemotherapy or chemoradiation)
  • 4Able to read and speak English
  • 5Do not meet recommended exercise levels as defined by The American College of Sports Medicine

Exclusion Criteria

  • 1History of metastatic or other primary cancer
  • 2Serious mental health conditions (e.g., bipolar disorder, schizophrenia, major depression)
  • 3Certain chronic diseases (e.g., muscular-skeletal diseases that limit mobility, autoimmune diseases, uncontrolled diabetes, hypertension, renal disease (creatinine \> 2.5 mg/dL)
  • 4Unable to read/speak English

Locations

4 sites participating in this study

Emory University Hospital Midtown

Atlanta, Georgia 30308

Recruiting

Zahra A. Barandouzi, Ph.D.,MSN,RN

Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia 30322

Recruiting

Zahra A. Barandouzi, Ph.D.,MSN,RN

Emory Decatur Hospital

Decatur, Georgia 30033

Recruiting

Zahra A. Barandouzi, Ph.D.,MSN,RN

Data sourced from ClinicalTrials.govView on ClinicalTrials.gov →